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CTCF fences make good neighbours
CCCTC-binding factor (CTCF) sites are enriched at the boundaries of topologically associated domains (TADs), but their function within TADs is unclear. Removal of sub-TAD CTCF sites adjacent to the α-globin enhancers is now shown to result in inappropriate activation of neighbouring genes. Intra-TAD...
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| Publicado en: | Nat Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6247897/ https://ncbi.nlm.nih.gov/pubmed/28752854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3584 |
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