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CTCF fences make good neighbours

CCCTC-binding factor (CTCF) sites are enriched at the boundaries of topologically associated domains (TADs), but their function within TADs is unclear. Removal of sub-TAD CTCF sites adjacent to the α-globin enhancers is now shown to result in inappropriate activation of neighbouring genes. Intra-TAD...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Cell Biol
Egile Nagusiak: Krivega, Ivan, Dean, Ann
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247897/
https://ncbi.nlm.nih.gov/pubmed/28752854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3584
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