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The HYDROPHOBE Challenge: A Joint Experimental and Computational Study on the Host-Guest Binding of Hydrocarbons to Cucurbiturils Allowing Explicit Evaluation of Guest Hydration Free Energy Contributions

The host-guest complexation of hydrocarbons (22 guest molecules) with cucurbit[7]uril (CB7) was investigated in aqueous solution. Association constants were determined by using the indicator displacement strategy, which allows binding constant determinations also for poorly water-soluble (hydrophobi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Phys Chem B
Prif Awduron: Assaf, Khaleel I., Florea, Mara, Antony, Jens, Henriksen, Niel M., Yin, Jian, Hansen, Andreas, Qu, Zheng-wang, Sure, Rebecca, Klapstein, Dieter, Gilson, Michael K., Grimme, Stefan, Nau, Werner M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247792/
https://ncbi.nlm.nih.gov/pubmed/29140701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b09175
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