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Computational Modeling of Oxidative Stress in Fatty Livers Elucidates the Underlying Mechanism of the Increased Susceptibility to Ischemia/Reperfusion Injury

QUESTION: Donor liver organs with moderate to high fat content (i.e. steatosis) suffer from an enhanced susceptibility to ischemia/reperfusion injury (IRI) during liver transplantation. Responsible for the cellular injury is an increased level of oxidative stress, however the underlying mechanistic...

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Détails bibliographiques
Publié dans:Comput Struct Biotechnol J
Auteurs principaux: Schleicher, Jana, Dahmen, Uta
Format: Artigo
Langue:Inglês
Publié: Research Network of Computational and Structural Biotechnology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247397/
https://ncbi.nlm.nih.gov/pubmed/30505404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2018.10.013
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