Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

Chitin is an essential component of the cell wall of Cryptococcus neoformans conferring structural rigidity and integrity under diverse environmental conditions. Chitin deacetylase genes encode the enyzmes (chitin deacetylases [Cdas]) that deacetylate chitin, converting it to chitosan. The functiona...

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Vydáno v:mBio
Hlavní autoři: Upadhya, Rajendra, Baker, Lorina G., Lam, Woei C., Specht, Charles A., Donlin, Maureen J., Lodge, Jennifer K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247093/
https://ncbi.nlm.nih.gov/pubmed/30459196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02087-18
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