Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity

A notable proportion of Salmonella-associated gastroenteritis in the United States is attributed to Salmonella enterica serovar Typhimurium. We have previously shown that live-attenuated S. Typhimurium vaccine candidate CVD 1921 (I77 ΔguaBA ΔclpP) was safe and immunogenic in rhesus macaques but was...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Higginson, Ellen E., Ramachandran, Girish, Panda, Aruna, Shipley, Steven T., Kriel, Edwin H., DeTolla, Louis J., Lipsky, Michael, Perkins, Darren J., Salerno-Goncalves, Rosangela, Sztein, Marcelo B., Pasetti, Marcela F., Levine, Myron M., Tennant, Sharon M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246900/
https://ncbi.nlm.nih.gov/pubmed/30249748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00440-18
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados