Altered expression of Phox2 transcription factors in the locus coeruleus in major depressive disorder mimicked by chronic stress and corticosterone treatment in vivo and in vitro.

Phox2a and Phox2b are two homeodomain transcription factors playing a pivotal role in the development of noradrenergic neurons during the embryonic period. However, their expression and function in adulthood remain to be elucidated. Using human postmortem brain tissues, rat stress models and culture...

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Publicado no:Neuroscience
Main Authors: Fan, Yan, Chen, Ping, Raza, Muhammad U., Szebeni, Attila, Szebeni, Katalin, Ordway, Gregory A., Stockmeier, Craig A., Zhu, Meng-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246807/
https://ncbi.nlm.nih.gov/pubmed/30315878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.09.038
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