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Development of a High-Throughput Biochemical Assay to Screen for Inhibitors of Aerobactin Synthetase IucA

Acquiring sufficient quantities of iron to support survival is often a critical limitation for pathogenic bacteria. To meet this demand, bacteria have evolved unique strategies to scavenge iron and circumvent the nutritional immunity exerted by their hosts. One common strategy, which is often a key...

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Dettagli Bibliografici
Pubblicato in:SLAS Discov
Autori principali: Bailey, Daniel C., Buckley, Brian P., Chernov, Mikhail V., Gulick, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246805/
https://ncbi.nlm.nih.gov/pubmed/29991301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218787140
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