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When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter

Mutational profiling has fundamentally changed our approach to patients with acute myeloid leukemia (AML). Patients with AML are routinely profiled for the presence of mutations in FLT3, NPM1, CEBPA, and, more recently, TP53. In this chapter, we review the role of mutational profiling to help define...

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Podrobná bibliografie
Vydáno v:Hematology Am Soc Hematol Educ Program
Hlavní autoři: Roloff, Gregory W., Griffiths, Elizabeth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246019/
https://ncbi.nlm.nih.gov/pubmed/30504289
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