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Potential new approaches to the management of the Hb Bart’s hydrops fetalis syndrome: the most severe form of α-thalassemia

The α-thalassemia trait, associated with deletions removing both α-globin genes from 1 chromosome (genotype ζ αα/ζ--), is common throughout Southeast Asia. Consequently, many pregnancies in couples of Southeast Asian origin carry a 1 in 4 risk of producing a fetus inheriting no functional α-globin g...

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Pubblicato in:Hematology Am Soc Hematol Educ Program
Autori principali: King, Andrew J., Higgs, Douglas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246003/
https://ncbi.nlm.nih.gov/pubmed/30504332
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