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The Attenuating Effects of 1,2,3,4,6 Penta-O-Galloyl-β-D-Glucose on Pro-Inflammatory Responses of LPS/IFNγ-activated BV-2 Microglial Cells through NFƙB and MAPK Signaling Pathways

BACKGROUND: Overactivated microglial cells exhibit chronic inflammatory response and can lead to the continuous production of pro-inflammatory cytokines, perpetuating inflammation, and ultimately resulting in neuronal injury. 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose (PGG), which is a naturally occurrin...

詳細記述

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書誌詳細
出版年:J Neuroimmunol
主要な著者: Mendonca, Patricia, Taka, Equar, Bauer, David, Reams, Renee R., Soliman, Karam F. A.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245951/
https://ncbi.nlm.nih.gov/pubmed/30236786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2018.09.004
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