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BLASSO: integration of biological knowledge into a regularized linear model

BACKGROUND: In RNA-Seq gene expression analysis, a genetic signature or biomarker is defined as a subset of genes that is probably involved in a given complex human trait and usually provide predictive capabilities for that trait. The discovery of new genetic signatures is challenging, as it entails...

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Bibliografische gegevens
Gepubliceerd in:BMC Syst Biol
Hoofdauteurs: Urda, Daniel, Aragón, Francisco, Bautista, Rocío, Franco, Leonardo, Veredas, Francisco J., Claros, Manuel Gonzalo, Jerez, José Manuel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245593/
https://ncbi.nlm.nih.gov/pubmed/30458775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0612-8
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