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AMPK-dependent and independent actions of P2X7 in regulation of mitochondrial and lysosomal functions in microglia

BACKGROUND: P2X7 is ubiquitously expressed in myeloid cells and regulates the pathophysiology of inflammatory diseases. Since mitochondrial function in microglia is highly associated with microglial functions in controlling neuronal plasticity and brain homeostasis, we interested to explore the role...

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Библиографические подробности
Опубликовано в: :Cell Commun Signal
Главные авторы: Sekar, Ponarulselvam, Huang, Duen-Yi, Hsieh, Shie-Liang, Chang, Shwu-Fen, Lin, Wan-Wan
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245559/
https://ncbi.nlm.nih.gov/pubmed/30458799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0293-3
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