A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions.

The Toxoplasma gondii locus mitochondrial association factor 1 (MAF1) encodes multiple paralogs, some of which mediate host mitochondrial association (HMA). Previous work showed that HMA was a trait that arose in T. gondii through neofunctionalization of an ancestral MAF1 ortholog. Structural analys...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Blank, Matthew L., Parker, Michelle L., Ramaswamy, Raghavendran, Powell, Cameron J., English, Elizabeth D., Adomako-Ankomah, Yaw, Pernas, Lena F., Workman, Sean D., Boothroyd, John C., Boulanger, Martin J., Boyle, Jon P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245547/
https://ncbi.nlm.nih.gov/pubmed/29505111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13947
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