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Design, Synthesis, and Antitumor Activities of Some Novel Substituted 1,2,3-Benzotriazines

A series of novel substituted 1,2,3-benzotriazines based on the structures of vatalanib succinate (PTK787) and vandetanib (ZD6474) were designed and synthesized. The antiproliferative effects of these compounds were tested on microvascular endothelial cells (MVECs) using the MTT assay. Introduction...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lv, Jin-Ling, Wang, Rui, Liu, Dan, Guo, Gang, Jing, Yong-Kui, Zhao, Lin-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245182/
https://ncbi.nlm.nih.gov/pubmed/18596667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules13061427
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