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Ferroquine, an Ingenious Antimalarial Drug –Thoughts on the Mechanism of Action

Ferroquine (FQ or SR97193) is a novel antimalarial drug candidate, currently in development at Sanofi-Aventis. In contrast to conventional drugs, FQ is the first organometallic drug: a ferrocenyl group covalently flanked by a 4-aminoquinoline and a basic alkylamine. FQ is able to overcome the CQ res...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Dubar, Faustine, Khalife, Jamal, Brocard, Jacques, Dive, Daniel, Biot, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245066/
https://ncbi.nlm.nih.gov/pubmed/19020475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules13112900
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