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Berberine Suppresses TNF-α-induced MMP-9 and Cell Invasion through Inhibition of AP-1 Activity in MDA-MB-231 Human Breast Cancer Cells

Invasion of cancer cell induced by matrix metalloproteinase-9 (MMP-9) is one of pivotal steps in cancer metastasis. Herein, we investigated how cell invasion was regulated by berberine (BBR), an isoquinoline derivative alkaloid compound, in MDA-MB-231 human breast cancer cells. The basal level of MM...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Kim, Sangmin, Choi, Jae Hyuck, Kim, Jong Bin, Nam, Seok Jin, Yang, Jung-Hyun, Kim, Jung-Han, Lee, Jeong Eon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244848/
https://ncbi.nlm.nih.gov/pubmed/19052522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules13122975
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