The paracrine effects of human induced pluripotent stem cells promote bone-like structures via the upregulation of BMP expression in a mouse ectopic model

Use of human induced pluripotent stem cells (h-iPSCs) for bone tissue engineering is most appealing, because h-iPSCs are an inexhaustible source of osteocompetent cells. The present study investigated the contribution of undifferentiated h-iPSCs and elucidated aspects of the underlying mechanism(s)...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Oudina, Karim, Paquet, Joseph, Moya, Adrien, Massourides, Emmanuelle, Bensidhoum, Morad, Larochette, Nathanaël, Deschepper, Mickael, Pinset, Christian, Petite, Hervé
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244408/
https://ncbi.nlm.nih.gov/pubmed/30459360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35546-6
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