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C-Terminal Residue of Ultrashort Peptides Impacts on Molecular Self-Assembly, Hydrogelation, and Interaction with Small-Molecule Drugs

Single molecular changes on a tripeptide can have dramatic effects on their self-assembly and hydrogelation. Herein, we explore C-terminal residue variation on two consistent ultrashort peptide backbones, i.e. acetylated-Leu-Ile-Val-Ala-Gly-Xaa and acetylated-Ile-Val-Xaa (Xaa = His, Arg, Asn). The o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chan, Kiat Hwa, Lee, Wei Hao, Ni, Ming, Loo, Yihua, Hauser, Charlotte A. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244206/
https://ncbi.nlm.nih.gov/pubmed/30459362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35431-2
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