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Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice

We investigated the different patterns of neurodegeneration and glia activation in CA1 and CA3 hippocampal areas of TgCRND8 mice. The main feature of this transgenic model is the rapid development of the amyloid pathology, which starts already at 3 months of age. We performed immunohistochemical ana...

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Bibliographische Detailangaben
Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Ugolini, Filippo, Lana, Daniele, Nardiello, Pamela, Nosi, Daniele, Pantano, Daniela, Casamenti, Fiorella, Giovannini, Maria Grazia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243135/
https://ncbi.nlm.nih.gov/pubmed/30483118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00372
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