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Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

Flow of cerebrospinal fluid (CSF) through perivascular spaces (PVSs) in the brain is important for clearance of metabolic waste. Arterial pulsations are thought to drive flow, but this has never been quantitatively shown. We used particle tracking to quantify CSF flow velocities in PVSs of live mice...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Mestre, Humberto, Tithof, Jeffrey, Du, Ting, Song, Wei, Peng, Weiguo, Sweeney, Amanda M., Olveda, Genaro, Thomas, John H., Nedergaard, Maiken, Kelley, Douglas H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242982/
https://ncbi.nlm.nih.gov/pubmed/30451853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07318-3
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