Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions

The precise interplay between the mRNA codon and the tRNA anticodon is crucial for ensuring efficient and accurate translation by the ribosome. The insertion of RNA nucleobase derivatives in the mRNA allowed us to modulate the stability of the codon-anticodon interaction in the decoding site of bact...

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Publicado no:Nat Commun
Main Authors: Hoernes, Thomas Philipp, Faserl, Klaus, Juen, Michael Andreas, Kremser, Johannes, Gasser, Catherina, Fuchs, Elisabeth, Shi, Xinying, Siewert, Aaron, Lindner, Herbert, Kreutz, Christoph, Micura, Ronald, Joseph, Simpson, Höbartner, Claudia, Westhof, Eric, Hüttenhofer, Alexander, Erlacher, Matthias David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242847/
https://ncbi.nlm.nih.gov/pubmed/30451861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07321-8
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