Chemoselective Dual Labeling of Native and Recombinant Proteins

[Image: see text] The attachment of two different functionalities in a site-selective fashion represents a great challenge in protein chemistry. We report site specific dual functionalizations of peptides and proteins capitalizing on reactivity differences of cysteines in their free (thiol) and prot...

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Publicat a:Bioconjug Chem
Autors principals: Agrawalla, Bikram Keshari, Wang, Tao, Riegger, Andreas, Domogalla, Matthias P., Steinbrink, Kerstin, Dörfler, Thilo, Chen, Xi, Boldt, Felix, Lamla, Markus, Michaelis, Jens, Kuan, Seah Ling, Weil, Tanja
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242188/
https://ncbi.nlm.nih.gov/pubmed/29231709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00675
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