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Enhanced anticancer activity and intracellular uptake of paclitaxel-containing solid lipid nanoparticles in multidrug-resistant breast cancer cells

PURPOSE: The aim of this study was to show enhanced anticancer activity of paclitaxel (Ptx) incorporated into solid lipid nanoparticles (SLNs) and reveal reversal of multidrug resistance (MDR) by SLNs mediated by increased uptake through different entry mechanisms from that in drug-sensitive cells....

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Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Xu, Wenting, Bae, Eun Ju, Lee, Mi-Kyung
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241869/
https://ncbi.nlm.nih.gov/pubmed/30532538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S182621
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