Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

Despite a growing body of evidence, the role of the gut microbiome in cardiovascular diseases (CVDs) is still unclear. Here we present a systems-genome-wide and metagenome-wide association study on plasma concentrations of 92 CVD-related proteins in the population cohort Lifelines-DEEP. We identifie...

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Gepubliceerd in:Nat Genet
Hoofdauteurs: Zhernakova, Daria V., Le, Trang H., Kurilshikov, Alexander, Atanasovska, Biljana, Bonder, Marc Jan, Sanna, Serena, Claringbould, Annique, Võsa, Urmo, Deelen, Patrick, Franke, Lude, de Boer, Rudolf A., Kuipers, Folkert, Netea, Mihai G., Hofker, Marten H., Wijmenga, Cisca, Zhernakova, Alexandra, Fu, Jingyuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241851/
https://ncbi.nlm.nih.gov/pubmed/30250126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0224-7
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