Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs

BACKGROUND: Gefitinib (Gef), an important epidermal growth factor receptor (EGFR), is used to treat lung cancer, but low water solubility and poor bioavailability severely limit its application in cancer therapy. METHODS: In this study, nanographene oxide (NGO) was decorated with hyaluronic acid (HA...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Liu, Jian, Zhang, Doudou, Lian, Shu, Zheng, Junxia, Li, Bifei, Li, Tao, Jia, Lee
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241762/
https://ncbi.nlm.nih.gov/pubmed/30532533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S173889
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