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IMPROVING HEALTHSPAN BY MANIPULATING SIRT6 LEVELS: HOW DOES IT WORK?
Mice over expressing the NAD+ dependent deacylases SIRT6 (MOSES mice) have extended lifespan along with significant improvement of their healthspan. In comparison to their wild-type (WT) littermates, old MOSES mice showed amelioration of a variety of age-related disorders, including: improved glucos...
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| Udgivet i: | Innov Aging |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6241426/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.036 |
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