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Degradable polymer prodrugs with adjustable activity from drug-initiated radical ring-opening copolymerization
Degradable polymer prodrugs based on gemcitabine (Gem) as an anticancer drug were synthesized by ‘drug-initiated’ nitroxide-mediated radical ring-opening copolymerization (NMrROP) of methacrylic esters and 2-methylene-4-phenyl-1,3-dioxolane (MPDL). Different structural parameters were varied to dete...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240899/ https://ncbi.nlm.nih.gov/pubmed/30542578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02256a |
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