Caricamento...
Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation
Increased light scattering in the eye lens due to aggregation of the long-lived lens proteins, crystallins, is the cause of cataract disease. Several mutations in the gene encoding human γD-crystallin (HγD) cause misfolding and aggregation. Cataract-associated substitutions at Trp(42) cause the prot...
Salvato in:
| Pubblicato in: | J Biol Chem |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240864/ https://ncbi.nlm.nih.gov/pubmed/30242128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004551 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|