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The mineralocorticoid receptor antagonist spironolactone reduces alcohol self- administration in female and male rats

Cortisol/corticosterone and the hypothalamic-pituitary-adrenal (HPA) axis serve an important role in modulating alcohol drinking behaviors. To date most alcohol research has focused on the functional involvement of corticosterone and the glucocorticoid receptor (GR), the primary receptor for cortico...

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Bibliographic Details
Published in:Pharmacol Biochem Behav
Main Authors: Makhijani, Viren H., Van Voorhies, Kalynn, Besheer, Joyce
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240486/
https://ncbi.nlm.nih.gov/pubmed/30171933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2018.07.011
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