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Activin A improves retinal pigment epithelial cell survival on stiff but not soft substrates

In several retinal degenerative disease pathologies, such as dry age-related macular degeneration (AMD), the retinal pigment epithelium (RPE) cell monolayer becomes dysfunctional. Promising tissue engineering treatment approaches implant RPE cells on scaffolds into the subretinal space. However, the...

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Pubblicato in:J Biomed Mater Res A
Autori principali: White, Corina E., Kwok, Bryan, Olabisi, Ronke M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240369/
https://ncbi.nlm.nih.gov/pubmed/30367547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36476
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