How much allopurinol does it take to get to target urate? Comparison of actual dose with creatinine clearance-based dose

OBJECTIVE: Allopurinol dosing has frequently been limited based on creatinine clearance (CrCL), resulting in failure to achieve target serum urate (SU). The aim of this analysis was to determine how many milligrams of allopurinol above the recommended CrCL-based dose (R+) are required to achieve tar...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Stamp, Lisa K., Chapman, Peter T., Barclay, Murray L., Horne, Anne, Frampton, Christopher, Tan, Paul, Drake, Jill, Dalbeth, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240322/
https://ncbi.nlm.nih.gov/pubmed/30446002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1755-0
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