Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells

Poor prognoses remain the most challenging aspect of hepatocellular carcinoma (HCC) therapy. Consequently, alternative therapeutics are essential to control HCC. This study investigated the anticancer effects of safranal against HCC using in vitro, in silico, and network analyses. Cell cycle and imm...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Al-Hrout, Ala’a, Chaiboonchoe, Amphun, Khraiwesh, Basel, Murali, Chandraprabha, Baig, Badriya, El-Awady, Raafat, Tarazi, Hamadeh, Alzahmi, Amnah, Nelson, David R., Greish, Yaser E., Ramadan, Wafaa, Salehi-Ashtiani, Kourosh, Amin, Amr
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240095/
https://ncbi.nlm.nih.gov/pubmed/30446676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34855-0
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