Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells

Poor prognoses remain the most challenging aspect of hepatocellular carcinoma (HCC) therapy. Consequently, alternative therapeutics are essential to control HCC. This study investigated the anticancer effects of safranal against HCC using in vitro, in silico, and network analyses. Cell cycle and imm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Al-Hrout, Ala’a, Chaiboonchoe, Amphun, Khraiwesh, Basel, Murali, Chandraprabha, Baig, Badriya, El-Awady, Raafat, Tarazi, Hamadeh, Alzahmi, Amnah, Nelson, David R., Greish, Yaser E., Ramadan, Wafaa, Salehi-Ashtiani, Kourosh, Amin, Amr
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240095/
https://ncbi.nlm.nih.gov/pubmed/30446676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34855-0
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