The impact of combined gene mutations in inhA and ahpC genes on high levels of isoniazid resistance amongst katG non-315 in multidrug-resistant tuberculosis isolates from China

Whole-genome sequencing was used to analyze the profiles of isoniazid (INH) resistance-related mutations among 188 multidrug-resistant strains of Mycobacterium tuberculosis (MDR-TB) and mono-INH-resistant isolates collected in a recent Chinese national survey. Mutations were detected in 18 structura...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Liu, Liguo, Jiang, Fengting, Chen, Lihong, Zhao, Bing, Dong, Jie, Sun, Lilian, Zhu, Yafang, Liu, Bo, Zhou, Yang, Yang, Jian, Zhao, Yanlin, Jin, Qi, Zhang, Xiaobing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240042/
https://ncbi.nlm.nih.gov/pubmed/30446638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0184-0
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