Astrocyte elevated gene-1 (AEG-1) regulates macrophage activation in hepatocellular carcinogenesis

Chronic inflammation is a known hallmark of cancer and is central to the onset and progression of hepatocellular carcinoma (HCC). Hepatic macrophages play a critical role in the inflammatory process leading to HCC. The oncogene Astrocyte elevated gene-1 (AEG-1) regulates NF-κB activation, and germli...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Robertson, Chadia L., Mendoza, Rachel G., Jariwala, Nidhi, Dozmorov, Mikhail, Mukhopadhyay, Nitai D., Subler, Mark A., Windle, Jolene J., Lai, Zhao, Fisher, Paul B., Ghosh, Shobha, Sarkar, Devanand
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239947/
https://ncbi.nlm.nih.gov/pubmed/30181179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0659
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