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Probing inhibition mechanisms of adenosine deaminase by using molecular dynamics simulations
Adenosine deaminase (ADA) catalyzes the deamination of adenosine, which is important in purine metabolism. ADA is ubiquitous to almost all human tissues, and ADA abnormalities have been reported in various diseases, including rheumatoid arthritis. ADA can be divided into two conformations based on t...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239307/ https://ncbi.nlm.nih.gov/pubmed/30444912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207234 |
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