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Nanotopography-Responsive Myotube Alignment and Orientation as a Sensitive Phenotypic Biomarker for Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy (DMD) is a fatal genetic disorder currently having no cure. Here we report that culture substrates patterned with nanogrooves and functionalized with Matrigel (or laminin) present an engineered cell microenvironment to allow myotubes derived from non-diseased, less-affect...
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| Publicado en: | Biomaterials |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239205/ https://ncbi.nlm.nih.gov/pubmed/30149230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.08.047 |
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