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The binding of Class II sRNA MgrR to two different sites on matchmaker protein Hfq enables efficient competition for Hfq and annealing to regulated mRNAs

MgrR is an Hfq-dependent sRNA, whose transcription is controlled by the level of Mg(2+) ions in Escherichia coli. MgrR belongs to Class II sRNAs because its stability in the cell is affected by mutations in Hfq differently than canonical, Class I sRNAs. Here, we examined the effect of mutations in R...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Kwiatkowska, Joanna, Wroblewska, Zuzanna, Johnson, Kenneth A., Olejniczak, Mikolaj
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239178/
https://ncbi.nlm.nih.gov/pubmed/30217864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.067777.118
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