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A sequence-based, deep learning model accurately predicts RNA splicing branchpoints

Experimental detection of RNA splicing branchpoints is difficult. To date, high-confidence experimental annotations exist for 18% of 3′ splice sites in the human genome. We develop a deep-learning-based branchpoint predictor, LaBranchoR, which predicts a correct branchpoint for at least 75% of 3′ sp...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Paggi, Joseph M., Bejerano, Gill
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239175/
https://ncbi.nlm.nih.gov/pubmed/30224349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.066290.118
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