Emergence of tigecycline resistance in Escherichia coli co-producing MCR-1 and NDM-5 during tigecycline salvage treatment

OBJECTIVE: Here, we report a case of severe infection caused by Escherichia coli that harbored mcr-1, bla (NDM-5), and acquired resistance to tigecycline during tigecycline salvage therapy. METHODS: Antimicrobial susceptibility testing, Southern blot hybridization, and complete genome sequence of th...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Wang, Qian, Zhang, Ping, Zhao, Dongdong, Jiang, Yan, Zhao, Feng, Wang, Yanfei, Li, Xi, Du, Xiaoxing, Yu, Yunsong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239116/
https://ncbi.nlm.nih.gov/pubmed/30519062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S179618
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