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Transcriptomic heterogeneity in multifocal prostate cancer

BACKGROUND. Commercial gene expression assays are guiding clinical decision making in patients with prostate cancer, particularly when considering active surveillance. Given heterogeneity and multifocality of primary prostate cancer, such assays should ideally be robust to the coexistence of unsampl...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Salami, Simpa S., Hovelson, Daniel H., Kaplan, Jeremy B., Mathieu, Romain, Udager, Aaron M., Curci, Nicole E., Lee, Matthew, Plouffe, Komal R., de la Vega, Lorena Lazo, Susani, Martin, Rioux-Leclercq, Nathalie, Spratt, Daniel E., Morgan, Todd M., Davenport, Matthew S., Chinnaiyan, Arul M., Cyrta, Joanna, Rubin, Mark A., Shariat, Shahrokh F., Tomlins, Scott A., Palapattu, Ganesh S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238741/
https://ncbi.nlm.nih.gov/pubmed/30385730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123468
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