Transcriptomic heterogeneity in multifocal prostate cancer

BACKGROUND. Commercial gene expression assays are guiding clinical decision making in patients with prostate cancer, particularly when considering active surveillance. Given heterogeneity and multifocality of primary prostate cancer, such assays should ideally be robust to the coexistence of unsampl...

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Publicado en:JCI Insight
Autores principales: Salami, Simpa S., Hovelson, Daniel H., Kaplan, Jeremy B., Mathieu, Romain, Udager, Aaron M., Curci, Nicole E., Lee, Matthew, Plouffe, Komal R., de la Vega, Lorena Lazo, Susani, Martin, Rioux-Leclercq, Nathalie, Spratt, Daniel E., Morgan, Todd M., Davenport, Matthew S., Chinnaiyan, Arul M., Cyrta, Joanna, Rubin, Mark A., Shariat, Shahrokh F., Tomlins, Scott A., Palapattu, Ganesh S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238741/
https://ncbi.nlm.nih.gov/pubmed/30385730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123468
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