Secretion of tumoricidal human tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by recombinant Lactococcus lactis: optimization of in vitro synthesis conditions

BACKGROUND: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively eliminates tumor cells. However, the short biological half-life of this molecule limits its potential use in the clinic. Our aim was to construct a recombinant strain of nonpathogenic Lactococcus lactis bacteria...

Full description

Saved in:
Bibliographic Details
Published in:Microb Cell Fact
Main Authors: Ciaćma, Katarzyna, Więckiewicz, Jerzy, Kędracka-Krok, Sylwia, Kurtyka, Magdalena, Stec, Małgorzata, Siedlar, Maciej, Baran, Jarek
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238363/
https://ncbi.nlm.nih.gov/pubmed/30446013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1028-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items