Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells

Background: Chemotherapy is the main treatment for triple-negative breast cancer (TNBC), which lack molecular markers for diagnosis and therapy. Cancer cells activate chemoresistant pathways and lead to therapeutic failure for patients with TNBC. Several kinases have been identified as chemoresistan...

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Vydáno v:Front Pharmacol
Hlavní autoři: Tzeng, Yen-Dun Tony, Liu, Pei-Feng, Li, Ju-Yueh, Liu, Li-Feng, Kuo, Soong-Yu, Hsieh, Chiao-Wei, Lee, Cheng-Hsin, Wu, Chih-Hsuan, Hsiao, Michael, Chang, Hong-Tai, Shu, Chih-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238227/
https://ncbi.nlm.nih.gov/pubmed/30473665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01285
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