Characterisation of a diazinon-metabolising glutathione S-transferase in the silkworm Bombyx mori by X-ray crystallography and genome editing analysis

Previously, we found an unclassified glutathione S-transferase 2 (bmGSTu2) in the silkworm Bombyx mori that conjugates glutathione to 1-chloro-2,4-dinitrobenzene and also metabolises diazinon, an organophosphate insecticide. Here, we provide a structural and genome-editing characterisation of the di...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Yamamoto, Kohji, Higashiura, Akifumi, Hirowatari, Aiko, Yamada, Naotaka, Tsubota, Takuya, Sezutsu, Hideki, Nakagawa, Atsushi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237972/
https://ncbi.nlm.nih.gov/pubmed/30443011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35207-8
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