Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways

Besides their well-known roles in digestion and fat solubilization, bile acids (BAs) have been described as signaling molecules activating the nuclear receptor Farnesoid-X-receptor (FXRα) or the G-protein-coupled bile acid receptor-1 (GPBAR-1 or TGR5). In previous reports, we showed that BAs decreas...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Baptissart, Marine, Sèdes, Lauriane, Holota, Hélène, Thirouard, Laura, Martinot, Emmanuelle, de Haze, Angélique, Rouaisnel, Betty, Caira, Françoise, Beaudoin, Claude, Volle, David H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237852/
https://ncbi.nlm.nih.gov/pubmed/30443025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34863-0
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