Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway

Mucins are heavily glycosylated proteins that play critical roles in the pathogenesis of tumour malignancies. Pancreatic ductal adenocarcinoma (PDAC) is characterised by the aberrant expression of mucins. However, the role of mucin (MUC) 20 in PDAC remains unclear. PDAC is usually surrounded by a de...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Chen, Syue-Ting, Kuo, Ting-Chun, Liao, Ying-Yu, Lin, Mei-Chun, Tien, Yu-Wen, Huang, Min-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237765/
https://ncbi.nlm.nih.gov/pubmed/29993037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0403-0
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