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High‐efficient bacterial production of human ApoA‐I amyloidogenic variants
Apolipoprotein A‐I (ApoA‐I)‐related amyloidosis is a rare disease caused by missense mutations in the APOA1 gene. These mutations lead to protein aggregation and abnormal accumulation of ApoA‐I amyloid fibrils in heart, liver, kidneys, skin, nerves, ovaries, or testes. Consequently, the carriers are...
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| Publicado no: | Protein Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237697/ https://ncbi.nlm.nih.gov/pubmed/30291643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3522 |
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