Adenosine deaminase inhibition suppresses progression of 4T1 murine breast cancer by adenosine receptor‐dependent mechanisms

The activity of a cell‐surface ecto‐adenosine deaminase (eADA) is markedly increased in the endothelial activation and vascular inflammation leading to decreased adenosine concentration and alterations in adenosine signalling. Depending on the specific pathway activated, extracellular purines mediat...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Kutryb‐Zajac, Barbara, Koszalka, Patrycja, Mierzejewska, Paulina, Bulinska, Alicja, Zabielska, Magdalena A., Brodzik, Karolina, Skrzypkowska, Aleksandra, Zelazek, Lukasz, Pelikant‐Malecka, Iwona, Slominska, Ewa M., Smolenski, Ryszard T.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237598/
https://ncbi.nlm.nih.gov/pubmed/30291675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13864
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