Influenza-mediated reduction of lung epithelial ion channel activity leads to dysregulated pulmonary fluid homeostasis

Severe influenza (IAV) infection can develop into bronchopneumonia and edema, leading to acquired respiratory distress syndrome (ARDS) and pathophysiology. Underlying causes for pulmonary edema and aberrant fluid regulation largely remain unknown, particularly regarding the role of viral-mediated me...

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Vydáno v:JCI Insight
Hlavní autoři: Brand, Jeffrey D., Lazrak, Ahmed, Trombley, John E., Shei, Ren-Jay, Adewale, A. Timothy, Tipper, Jennifer L., Yu, Zhihong, Ashtekar, Amit R., Rowe, Steven M., Matalon, Sadis, Harrod, Kevin S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237450/
https://ncbi.nlm.nih.gov/pubmed/30333319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123467
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