Increased expression of ATP12A proton pump in cystic fibrosis airways

Proton secretion mediated by ATP12A protein on the surface of the airway epithelium may contribute to cystic fibrosis (CF) lung disease by favoring bacterial infection and airway obstruction. We studied ATP12A in fresh bronchial samples and in cultured epithelial cells. In vivo, ATP12A expression wa...

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Pubblicato in:JCI Insight
Autori principali: Scudieri, Paolo, Musante, Ilaria, Caci, Emanuela, Venturini, Arianna, Morelli, Patrizia, Walter, Christine, Tosi, Davide, Palleschi, Alessandro, Martin-Vasallo, Pablo, Sermet-Gaudelus, Isabelle, Planelles, Gabrielle, Crambert, Gilles, Galietta, Luis J.V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237449/
https://ncbi.nlm.nih.gov/pubmed/30333310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123616
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