Knockdown of lncRNA KCNQ1OT1 suppresses the adipogenic and osteogenic differentiation of tendon stem cell via downregulating miR-138 target genes PPARγ and RUNX2

The study aimed to investigate the mechanism and biological roles of long noncoding RNAKCNQ1OT1 in adipogenic and osteogenic differentiation of tendon stem cell. In this study, tendon injury mice model was established to detect the expression of lncRNA KCNQ1OT1, miR-138, peroxisome proliferator-acti...

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Detalles Bibliográficos
Publicado en:Cell Cycle
Autores principales: Yu, Yang, Chen, Ying, Zhang, Xiaolei, Lu, Xiaolang, Hong, Jianjun, Guo, Xiaoshan, Zhou, Dongsheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237432/
https://ncbi.nlm.nih.gov/pubmed/30321077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1534510
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